Anti-IgA IgG Antibodies, Blood (Referred Out) - Saskatoon
Discipline
Biochemistry
Overview
Description
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Evaluation of patients with a history of a severe transfusion reaction with signs of anaphylaxis
- If testing is due to a transfusion reaction, the specimen should be drawn approximately a minimum of 10 days after the reaction. Testing performed on serum drawn immediately after a reaction may be falsely negative as transfused IgA may deplete anti-IgA antibodies.
Alias
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Anti-IgA
- Anti-Immunoglobulin A
Specimen Information
Specimen types accepted
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Serum
Specimen collection container
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Preferred collection container: Gold (gel)
- Alternative collection container: Red (non-gel)
Required volume
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Optimal volume: full 4.5 mL collection tube
- Minimum volume: 0.5 mL serum
(Submitting the minimum volume makes it impossible to repeat the test or perform confirmatory/reflex testing. In some situations, a minimum volume may require a second collection.)
- Pediatric volume: 0.4 mL serum
Transport and stability
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Stable for 28 days frozen or refrigerated
Rejection criteria
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Gross Lipemia
- Specimen received where the proper collection protocols were not followed
- Pathology and Laboratory Medicine Acceptance and Rejection Criteria
Testing Information
Clinical interpretation
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Evaluation of patients with a history of a severe transfusion reaction with signs of anaphylaxis
- Identification of patients who require IgA-free blood products
Performance
Methodology
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Nephelometry
Days/times performed
| Availability |
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| Testing site |
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Maximum laboratory time
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14 day turnaround time by testing laboratory
Last Updated: October 3, 2024