Chromogranin A, Blood (Referred Out) - Saskatoon
Discipline
Biochemistry
Specimen Information
Specimen types accepted
- Serum
Specimen collection container
- Preferred collection container: Gold (gel) 5.0mL
- Alternative collection container: Red (no additive) 6.0mL
Collection procedure
- Centrifuge, aliquot and freeze serum within 24 hours of collection.
Required volume
- Optimal volume: 1 mL serum
Rejection criteria
- Specimens received where the collection protocols were not followed
- Pathology and Laboratory Medicine Acceptance and Rejection Criteria
Testing Information
Clinical interpretation
- Result interpretation should be correlated with clinical and other laboratory findings.
Performance
Days/times performed
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Maximum laboratory time
- 15 day turnaround time by referral laboratory
Other information
- Aids in monitoring of carcinoid tumors
- Proton pump inhibitor can lead to significant elevations of chromogranin A. H2-receptor antagonist can be used at modest doses.
- Samples with cloudiness, hemolysis, hyperlipidemia or containing fibrin may give inaccurate results
- Impaired hepatic or renal function could elevate chromogranin A.
- Various non-neuroendocrine tumors might also associated with elevation of chromogranin A.
Last Updated: October 9, 2024