Primidone, Plasma/Serum (Referred Out) - Saskatoon
Discipline
Biochemistry
Overview
Description
- Collect immediately before next oral dose for trough concentration at the steady state
Alias
- Mysoline
Specimen Information
Specimen types accepted
- Serum or plasma
Specimen collection container
- Preferred collection container: Red (non-gel)
- Alternative collection container: Dark Green (non-gel lithium heparin)
- Alternative collection container: Lavender (EDTA)
Required volume
- Optimal volume: 4.0 mL full collection tube
- Minimum volume: 1 mL serum or plasma
(Submitting the minimum volume makes it impossible to repeat the test or perform confirmatory/reflex testing. In some situations, a minimum volume may require a second collection.)
Transport and stability
- Centrifuge and remove serum from cells as soon as possible
Rejection criteria
- Specimens received where the proper collection protocols were not followed
- Pathology and Laboratory Medicine Acceptance and Rejection Criteria
Testing Information
Reference ranges/critical values
- Primidone: therapeutic: 23-46 umol/L; toxic: > 115 umol/L;
- Phenobarb: toxic: > 216 umol/L
Performance
Days/times performed
Availability |
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Testing Site |
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Maximum laboratory time
- One day turnaround time by testing laboratory
Other information
- This test includes both parent drug and metabolite (i.e, phenobarbital)
Last Updated: October 7, 2024