Sialic Acid (Total and Free), Urine (Referred Out) - Saskatoon
Discipline
Biochemistry
Overview
Description
Testing Ordering Requirements
Forms Required
- Miscellaneous Specimen Requisition Form #101878 or SHR Laboratory Medicine Community Laboratory Requisition Form #101064 or Acute Care Phlebotomy Requisition Form #101062
Alias
- N-Acetylneuraminic acid
- NANA
Specimen Information
Specimen types accepted
- Random urine, first morning void if possible
Specimen collection container
- Preferred Collection Container: Sterile Wide Mouth Screw Cap Container (Pink Top)
Required volume
- Optimal Volume: 10 mL urine
- Minimum Volume/Pediatric Volume: 10 mL urine
(Submitting the minimum volume makes it impossible to repeat the test or perform confirmatory/reflex testing. In some situations, a minimum volume may require a second collection)
Transport and stability
- Send specimen to SPH lab on an ice pack
- Freeze immediately upon receipt in the lab
- Ship frozen to referral laboratory
Rejection criteria
- If specimen thaws it is unsuitable for analysis
- Specimens received where the proper collection protocols were not followed
- Pathology and Laboratory Medicine Acceptance and Rejection Criteria
Testing Information
Relevant clinical history
- Family history
- Must include diagnosis and/or patient symptoms on the requisition
Clinical interpretation
- Result interpretation should be correlated with clinical and other laboratory findings
Performance
Methodology
- Available upon request
Days/times performed
Availability |
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Testing Site |
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Maximum laboratory time
Results Reporting
- 3-4 week turnaround time by referral laboratory
Other information
Additional Comments
- For the investigation of neuraminidase deficiency (including galactosialidosis), lysosomal free sialic acid storage disorders and sialuria
- Hemolytic uremic syndrome, pregnancy, renal failure, bladder tumors as well as type 2 diabetes could lead to elevated sialic acid
Last Updated: October 3, 2024