Tacrolimus, Blood - Saskatoon

Discipline

Biochemistry

Overview

Description

Ordering Recommendation

For trough level tests, collect specimen immediately prior to the next dose

Test Ordering Requirements

Forms Required

Miscellaneous Specimen Requisition Form #101878 or

SHR Laboratory Medicine Community Laboratory Requisition Form #101064 or

Acute Care Phlebotomy Requisition Form #101062

If a Pharmacokinetic Study is requested:

Contact the Clinical Biochemist on call via RUH switchboard (306)655-1000.
Fill out a Pharmacokinetic (PK) Study-Tacrolimus and Mycophenolate-Mofetil Requisition. form#4473

Alias

FK-506

Specimen Information

Specimen types accepted

Whole Blood

Specimen collection container

Preferred Collection Container: Lavender (EDTA)

Collection procedure

Do not collect from I.V. line through which Tacrolimus is administered.

Required volume

Optimal Volume: 4.0 mL Full collection tube
Minimum Volume: 0.5 mL

(Submitting the minimum volume makes it impossible to repeat the test or perform confirmatory/reflex testing. In some situations, a minimum volume may require a second collection.)

Transport and stability

7 days at 2 – 8 ºC

Rejection criteria

Specimens received where the proper collection protocols were not followed
Pathology and Laboratory Medicine Acceptance and Rejection Criteria

Testing Information

Relevant clinical history

Relevant Recent Medication History

Note on requisition the dosage, date and time when medication was given

Performance

Methodology

Electrochemiluminescence Immunoassay

Days/times performed

Availability	Tacrolimus on inpatients shall be performed once per day seven days a week. Results shall be available at 2:30 p.m. Outpatients are available once per day Monday to Friday All other stat requests must be cleared by the Clinical Biochemist on call
Testing Site	SPH

Maximum laboratory time

Results Reporting

Inpatients within 24 hours
Outpatients with 72 hours

Specimen retention time

3 days

Last Updated: October 3, 2024