HLA-B*57:01 - Provincial
Discipline
Histocompatibility and Immunogenetics (HLA)
Overview
Description
- This test will only be run once per patient, even when ordered by a different ordering physician.
- Contact Positive Living Program (Public Health Services) for information regarding requisition and to verify patient has not been tested.
Specimen Information
Specimen types accepted
- Whole blood
Specimen collection container
- Preferred collection container: Lavender top (EDTA) or Yellow top (ACD-A)
Required volume
- Optimal volume: 4 mL
- Minimum volume: 1 mL
(Submitting the minimum volume makes it impossible to repeat the test or perform confirmatory/reflex testing. In some situations, a minimum volume may require a second collection.)
Transport and stability
- Stable for 7 days at 4 - 25°C
Rejection criteria
- Unlabeled, illegibly-labelled, mislabeled, or inadequately labelled specimens
- Original labeling must be present and visible
- Incomplete, inaccurate, or illegible information on the requisition
- Discrepancies between requisition patient information and specimen label information
- Collected by – required for all collections
- Date and time of collection
- Pathology and Laboratory Medicine Acceptance and Rejection Criteria
Testing Information
Relevant clinical history
- Diagnosis
Clinical interpretation
- Among people with HIV infection, a version of HLA-B designated HLA-B*5701 is associated with an extreme sensitivity to Abacavir.
Performance
Methodology
- Low and/or high resolution molecular typing (rSSO/SSP)
Days/times performed
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Maximum laboratory time
- 21 days
Specimen retention time
- Specimen (Extracted DNA) retained for one year.
Other information
- Forms required - HIL Test Request Form
Last Updated: July 4, 2024